Fusion of FDG-PET Image and Clinical Features for Prediction of Lung Metastasis in Soft Tissue Sarcomas

Table 2

SUV metrics features and Clinical features used in this study.

Type	Name	Description
SUV metrics	SUVmax	Maximum SUV of the tumour region
	SUVpeak	Average of the voxel with maximum SUV within the tumour region and its 26 connected neighbors
	SUVmean	Average SUV value of the tumour region
	aucCSH	Area under the curve of the cumulative SUV volume histogram describing the percentage of total tumour volume above a percentage threshold of maximum SUV
	PercentInactive	Percentage of the tumour region that is inactive. A threshold of ^2 followed by closing and opening morphological operations were used to differentiate active and inactive regions on FDG-PET scans
Textures	Global	Variance
		Skewness
		Kurtosis
	GLCM	Energy
		Contrast
		Entropy
		Homogeneity
		Correlation
		SumAverage
		Variance
		Dissimilarity
		AutoCorrelation
Textures	GLRLM	SRE (short run emphasis)
		LRE (long run emphasis)
		GLN (gray-level nonuniformity)
		RLN (run-length nonuniformity)
		RP (run percentage)
		LGRE (low gray-level run emphasis)
		HGRE (high gray-level run emphasis)
		SRLGE (short run low gray-level emphasis)
		SRHGE (short run high gray-level emphasis)
		LRLGE (long run low gray-level emphasis)
		LRHGE (long run high gray-level emphasis)
		GLV (gray-level variance)
		RLV (run-length variance)
	GLSZM	SZE (small-zone emphasis)
		LZE (large-zone emphasis)
		GLN (gray-level nonuniformity)
		ZSN (zone-size nonuniformity)
		ZP (zone percentage)
		LGZE (low gray-level zone emphasis)
		HGZE (high gray-level zone emphasis)
		SZLGE (small-zone low gray-level emphasis)
		SZHGE (small-zone high gray-level emphasis)
		LZLGE (large-zone low gray-level emphasis)
		LZHGE (large-zone high gray-level emphasis)
		GLV (gray-level variance)
		ZSV (zone-size variance)
	NGTDM	Coarseness
		Contrast
		Busyness
		Complexity
		Strength
Clinical	Age	Age
	Sex	Male
		Female
	Treatment
		Status	Alive
			Alive with disease
	Dead
	Grade	High
		Intermediate
		Low
	MSKCC type	Liposarcoma
		Leiomyosarcoma
		Synovial sarcoma
		Malignant fibrous histiocytomas
		Extraskeletal bone sarcoma
		Fibrosarcoma
		Other