miR-152-3p Affects the Progression of Colon Cancer via the KLF4/IFITM3 Axis
miR-152-3p targets KLF4 and decreases its expression. (a) Binding sites of miR-152-3p on KLF4 3UTR were predicted by the bioinformatics method. (b) Dual-luciferase assay was done for the validation of the targeting relationship between miR-152-3p and KLF4. (c) Western blot was conducted to test the protein expression of KLF4 and IFITM3 in each treatment group ( means ).
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