Research Article

Efficacy and Safety of Immunosuppressant Therapy for Noninfectious Uveitis: A Systematic Review and Meta-Analysis

Table 1

Baseline information of included literature.

AuthorYearType of studyIntervention (treatment vs. control)Patients (treatment/control)Female (treatment/control)Efficacy (yes/no) treatment vs. control

Nguyen et al.2016RCT, DBAdalimumab vs. placebo115/11166/7270/45 vs. 50/61
Jaffe et al.2016RCT, DBAdalimumab vs. placebo
Ramanan et al.2017RCT, DBAdalimumab vs. placebo60/3047/2344/16 vs. 12/18
Quartier et al.2017RCT, DBAdalimumab vs. placebo16/1515/139/7 vs. 3/12
Cecchin et al.2018Prospective studyAdalimumab vs. infliximab95/5916/1557/38 vs. 12/47
Heissigerová et al.2018RCT, DBSarilumab vs. placebo38/2023/1329/9 vs. 15/5
Rathinam et al.2019RCT, SBMethotrexate vs. mycophenolate mofetil107/10975/6064/43 vs. 56/53

RCT: randomized controlled trial; DB: double-blind; SB: single-blind; DMARDs: disease-modifying antirheumatic drugs.