Establishment of an Immune-Related Gene Signature for Risk Stratification for Patients with Glioma

Table 1

Clusters of PPI network using the MCODE algorithm.

Cluster	Nodes	Edges	Score	Gene symbol
A	18	153	18	F8, FIGF, TGFB1, VEGFB, TIMP1, EGF, TGFB2, TGFB3, IGF1, VEGFC, HGF, THBS1, ALB, FN1, AHSG, VEGFA, PDGFB, and VWF
B	16	58	7.733	CYR61, CUL5, SOCS3, IL6, TCEB1, IGFBP1, IGFBP3, IGFBP5, RBX, SPP1, CUL2, IGFBP4, VHL, TCEB2, SOCS2, and RNF7
C	15	52	7.429	PLCG1, PDGFRB, STAT5B, SYK, FLT1, VAV1, PGF, KDR, LCP2, FYN, STAT5A, GAB1, STAT1, PTPN11, and EGFR
D	6	15	6	RAMP1, RAMP2, ADM, CALCRL, RAMP3, and CALCA

PPI: protein-protein interaction; MCODE: molecular complex detection; bold texts indicate differentially expressed genes in the PPI network.