Research Article

[Retracted] Detection of BRCA1/2 Mutation and Analysis of Clinicopathological Characteristics in 141 Cases of Ovarian Cancer

Table 3

Association of the BRCA1/2-mutations with clinicopathologic characteristics in 141 ovarian cancer patients.

Clinicopathologic characteristicsBRCA1/2-mutation
Type (cases)
BRCA1/2-wild type (cases) value

Age (year)0.218
 ≤407.4% (2/27)4.4% (5/114)
 40-4937% (10/27)21.0% (24/114)
 50-5937% (10/27)44.8% (51/114)
 ≥6018.5% (5/27)29.8% (34/114)
FIGO staging0.649
 I-II18.5% (5/27)16.7% (19/114)
 III-IV77.8% (21/27)64.9% (74/114)
 Unknown3.7% (1/27)18.4% (21/114)
Serum CA1250.426
 High81.5% (22/27)77.2% (88/114)
 Normal18.5% (5/27)22.8% (26/114)
Family history0.134
 Presence14.8% (4/27)6.1% (7/114)
 Absence85.2% (23/27)93.9% (107/114)
Personal history0.682
 Presence14.8% (4/27)4.4% (5/114)
 Absence85.2% (23/27)95.6% (109/114)
Distant metastasis0.002
 Presence70.4% (19/27)37.7% (43/114)
 Absence29.6% (8/27)62.3% (71/114)
Ki67 protein0.869
 Positive66.7% (18/27)45.6% (52/114)
 Negative11.1% (3/27)13.2% (15/114)
 Unknown22.2% (6/27)41.2% (47/114)