Delivery of miR-224-5p by Exosomes from Cancer-Associated Fibroblasts Potentiates Progression of Clear Cell Renal Cell Carcinoma

Figure 4

Overexpression of miR-224-5p promotes proliferation, migration, and invasion of ccRCC cells and inhibits cell apoptosis. (a) CCK-8 was performed to determine cell proliferation after miR-224-5p was overexpressed; (b) flow cytometry was used to detect cell apoptosis after miR-224-5p was overexpressed; (c, d) Transwell assay was performed to determine the invasion (c) and migration (d) of cells after transfection with miR-224-5p mimic or NC mimic (100x). .

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