|
Feature | COVID-19 | SARS | MERS |
|
Clinical sign or symptom | | | |
Fever or chills | Yes | Yes | Yes |
Dyspnea | Yes | Yes | Yes |
Malaise | Yes | Yes | Yes |
Myalgia | Yes | Yes | Yes |
Headache | Yes | Yes | Yes |
Cough | Dry | Dry | Dry or productive |
Diarrhoea | Uncommon | Yes | Yes |
Nausea or vomiting | Uncommon | Yes | Yes |
Sore throat | Uncommon | Yes | Yes |
Arthralgia | | Yes | Uncommon |
Imaging finding | | | |
Acute phase | | | |
Initial imaging | | | |
Normal | 15–20% of patients | 15–20% of patients | 17% of patients |
Abnormalities | | | |
Common | Peripheral multifocal airspace opacities (GGO, consolidation, or both) on chest radiography and CT. | Peripheral multifocal airspace opacities (GGO, consolidation, or both) on chest radiography and CT. | Peripheral multifocal airspace opacities (GGO, consolidation, or both) on chest radiography and CT. |
Rare | Pneumothorax | Pneumothorax | Pneumothorax |
Not seen | Cavitation or lymphadenopathy | Cavitation or lymphadenopathy | Cavitation or lymphadenopathy |
Appearance | Bilateral, multifocal, basal airspace; normal chest radiography findings (15%) | Bilateral, multifocal basal airspace on chest radiography or CT (80%); isolated unilateral (20%) | Unilateral, focal (50%); multifocal (40%); diffuse (10%) |
Follow-up imaging appearance | Persistent or progressive airspace opacities | Unilateral, focal (25%); progressive (most common, can be unilateral and multifocal or bilateral with multifocal consolidation) | Extension into upper lobes or perihilar areas, pleural effusion (33%), interlobular septal thickening (26%) |
Indications of poor prognosis | Consolidation (vs. GGO) | Bilateral (like ARDS), for or more lung zones, progressive involvement after 12 d | Greater involvement of the lungs, pleural effusion, pneumothorax |
Chronic phase | Unknown, but pleural effusion and interlobar septal thickening have not yet been reported | | |
Transient reticular opacities | | Yes | Yes |
Air trapping | | Common (usually persistent) | |
Fibrosis | More than one-third of patients | Rare | One-third of patients |
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