Research Article

Research for Expression and Prognostic Value of GABRD in Colon Cancer and Coexpressed Gene Network Construction Based on Data Mining

Table 1

Networks of kinase, miRNA, and transcription factor targets of GABRD.

NetworksGene setDescriptionSizeLeading edge numberESNES valueFDR

Kinase targetKinase_WEE1WEE1 G2 checkpoint kinase54-0.92033-1.71920.00709220.17746
Kinase_NEK2NIMA-related kinase 285-0.74354-1.7460.0210530.18368
Kinase_PKMPyruvate kinase, muscle42-0.95009-1.7604≤0.0010.235
Kinase_CSNK1G2Casein kinase 1 gamma 2630.947651.52720.00263160.2712

miRNA targetTTCCGTT,MIR-1912990.644171.26990.104080.19167
ATACCTC,MIR-202166560.609661.27190.0020.19248
ATGCTGG,MIR-338104230.623961.27580.0060.19375
ATGTAGC,MIR-221,MIR-222133450.623961.27660.0040.19849
AACATTC,MIR-409-3P132320.608461.25870.0040080.19852

Transcription factor targetGKCGCNNNNNNNTGAYG_UNKNOWN5217-0.52265-2.0365≤0.0010
V$CEBP_01244710.618841.2806≤0.0010.028315
V$IRF1_01229720.621671.2947≤0.0010.028349
V$STAT5A_01231770.620771.2809≤0.0010.028362
V$TTF1_Q6243830.627741.2951≤0.0010.028446