RAMRSGL: A Robust Adaptive Multinomial Regression Model for Multicancer Classification

Table 4

Seven key genes selected by RAMRSGL on leukemia data.

Gene	Number group	Gene title	Annotation of gene function
CDK1	2	Cyclin-dependent kinase 1	Phosphorylation and dephosphorylation of CDK1-encoded proteins play an important role in cell cycle regulation.
LRRC14	24, 65	Leucine-rich repeat containing 14	LRRC14 negatively regulates NF-kappa B transcription factor activity and toll-like receptor signaling pathway.
MIF	51	Macrophage migration inhibitory factor	MIF encodes a lymphokine involved in cell-mediated immunity, immunomodulation, and inflammation.
Srpr	84	Signal recognition particle receptor	Srpr plays a role in signal recognition of particle binding.
DGUOK	46	Deoxyguanosine kinase	The protein encoded by DGUOK is responsible for phosphorylation of purine DNA in the mitochondrial matrix.
SRI	88	Sorcin	SRI encodes a calcium-binding protein that regulates intracellular calcium homeostasis.
HSPB1	105	Heat shock protein family B member 1	HSPB1 encodes proteins that play important roles in the differentiation of a variety of cell types.