Review Article

Seven Mathematical Models of Hemorrhagic Shock

Table 6

Variables and parameters of the cardiovascular model (adapted from Tab. 1 in Zenker et al. [13], p. 2082).

SymbolDescription

Heart rate
Duration of systole and diastole, respectively
Stroke work, work of heart in a cardiac cycle
Cardiac output
Stroke volume, volume of ejected blood in a cardiac cycle
End-systolic ventricular volume; end-diastolic ventricular volume
Constants describing passive empirical ventricular pressure/volume relationship
Hydraulic resistance to ventricular filling, with valve allowing unidirectional flow
End-diastolic pressure at the end of ventricular filling
Left ventricular pressure; arterial pressure; venous pressure
Ventricular volume; arterial volume; venous volume
Arterial and venous unstressed volume (at 0 mmHg of wall tension pressure), respectively
Total peripheral/systemic hydraulic vascular resistance
Arterial to venous compartment flow through capillary vessels
Preload recruitable stroke work, an index of how much contractility and stroke work increase with increasing diastolic filling
Arterial and venous compartment compliances, respectively
Baroreflex response time constant
Baroreflex feedback loop set point
Constant describing shape and maximal slope of logistic baroreflex nonlinearity