Angelica sinensis Polysaccharide Alleviates Myocardial Fibrosis and Oxidative Stress in the Heart of Hypertensive Rats

Figure 1

ASP treatment alleviates cardiac function in vivo. The rats were induced to hypertensive heart disease (HHD) rats by high-fat diet (HFD) randomly divided into three doses of ASP-treated groups and a vehicle-treated group. Meanwhile, the standard diet-fed rats were treated with distill water as a normal control group. (a) The body weight was measured during the experimental process. (b) Left ventricle function was measured including left ventricle end-diastolic volume (LVEDV), left ventricle end-diastolic diameter (LVEDD), left ventricle end-systolic diameter (LVESD) and left ventricular end-systolic volume (LVESV), left ventricular ejection fraction (EF), and left ventricular short axis shortening rate (FS). Three independent experiments were performed. The graph shows the calculated for at least three experiments. ^{or #}, ^{or ##}.

(a)

(b)