Angelica sinensis Polysaccharide Alleviates Myocardial Fibrosis and Oxidative Stress in the Heart of Hypertensive Rats

Figure 3

ASP treatment inhibits the apoptosis of cardiomyocytes in vivo. TUNEL staining assays were performed to demonstrate the apoptosis of cardiac myocytes in rat left ventricular tissues. The expression levels of Bax, Bcl-2, cleaved caspase-3, and cleaved caspase-9 were evaluated by performing RT-qPCR (b) and western blot assay (c) in the different sample groups. Protein expression levels relative to β-actin levels are shown. Three independent experiments were performed. The graph shows the calculated for at least three experiments. ^{or #}, ^{or ##}, and ^{or ###}.

(a)

(b)

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