Research Article

Bayesian Gene Selection Based on Pathway Information and Network-Constrained Regularization

Table 3

Description of top 18 genes of GSE4922.

Gene symbolDescriptionReference

SYCP3Synaptonemal complex protein 3[35]
CDKN2ACyclin dependent kinase inhibitor 2A[36]
PLB1
CTNNBIP1
Phospholipase B1
Catenin beta-interacting protein 1
[37]
[38]
GBE11,4-Alpha-glucan-branching enzyme 1[39]
SMURF1SMAD-specific E3 ubiquitin protein ligase 1[40]
NR1H4Nuclear receptor subfamily 1 group H member 4/
PDE11APhosphodiesterase 11A/
UGT1A1UDP glucuronosyltransferase family 1 member A1[41]
FGF19Fibroblast growth factor 19[42]
OR51B4Olfactory receptor family 51 subfamily B member 4[43]
RAB7ARAB7A, member RAS oncogene family[44]
SDHDSuccinate dehydrogenase complex subunit D[45]
IFNA8Interferon alpha 8/
VANGL2VANGL planar cell polarity protein 2[46]
UMPSUridine monophosphate synthetase/
CASP3Caspase 3[47]
SUFUSUFU negative regulator of hedgehog signaling[48]

The gene was reported as an oncogene in previous literatures.