Development and Validation of Prediction Model for High Ovarian Response in In Vitro Fertilization-Embryo Transfer: A Longitudinal Study

Table 1

Baseline characteristics of study population.

Variables, (%)	Total ()	Group		Statistic
		Training set ()	Testing set ()
Age, years,					0.389
BMI, kg/m^2,					0.317
Smoking history, (%)					0.351
Active smoking	6 (1.25)	5 (1.49)	1 (0.69)
Passive smoking	75 (15.63)	48 (14.29)	27 (18.75)
No	399 (83.13)	283 (84.23)	116 (80.56)
Type of infertility, (%)					0.089
Primary	174 (36.25)	130 (38.69)	44 (30.56)
Secondary	306 (63.75)	206 (61.31)	100 (69.44)
Pregnancy history, (%)					0.094
No	177 (36.88)	132 (39.29)	45 (31.25)
Yes	303 (63.13)	204 (60.71)	99 (68.75)
Age at menarche, years,					0.551
Mean menstrual cycle, days,					0.385
Duration of infertility, years,	3.00 (1.00, 4.00)	3.00 (2.00, 4.00)	3.00 (1.00, 4.50)		0.586
AFC,	15.00 (12.00, 20.00)	15.00 (12.00, 19.00)	15.00 (12.00, 20.00)		0.770
LH, mu/mL,	4.79 (3.61, 6.24)	4.79 (3.54, 6.02)	4.75 (3.72, 6.34)		0.212
MC3
E2, pmol/L,	36.18 (25.95, 46.42)	36.16 (26.26, 46.38)	36.60 (25.57, 46.49)		0.602
P, nmol/L,	0.39 (0.26, 0.59)	0.40 (0.26, 0.59)	0.35 (0.25, 0.56)		0.221
FSH, U/L,					0.186
AMH, ng/ml,	3.71 (2.46, 5.27)	3.68 (2.46, 5.25)	3.75 (2.46, 5.33)		0.914
Endometrial thickness, mm,					0.526
Group					0.952
Normal response	241 (50.21)	169 (50.30)	72 (50.00)
High response	239 (49.79)	167 (49.70)	72 (50.00)

BMI: body mass index; AFC: antral follicle count; LH: luteinizing hormone; MC3: menstrual cycle day 3; E2: estradiol; P: progesterone; FSH: follicle-stimulating hormone; AMH: anti-Müllerian hormone; : ; : median and quartile; : measured the degree of correlation between two categorical variables; : compared the difference between the two groups; : represented the rank sum test for the comparison of two samples.