Development and Validation of Prediction Model for High Ovarian Response in In Vitro Fertilization-Embryo Transfer: A Longitudinal Study

Table 3

Univariate analysis for the potential predictors of high ovarian response in IVF-ET.

Variables, (%)		S.E	Wald		OR	95% CI
						Lower	Upper
Age	-0.075	0.030	6.489	0.011	0.927	0.875	0.983
BMI	0.013	0.037	0.116	0.734	1.013	0.942	1.088
Smoking history
No					Ref
Active smoking	0.455	0.921	0.244	0.621	1.576	0.259	9.576
Passive smoking	0.217	0.313	0.478	0.489	1.242	0.672	2.294
Type of infertility
Primary					Ref
Secondary	-0.423	0.225	3.515	0.061	0.655	0.421	1.019
Pregnancy history
No					Ref
Yes	-0.270	0.224	1.449	0.229	0.764	0.492	1.185
Age at menarche	-0.115	0.092	1.572	0.210	0.891	0.745	1.067
Mean menstrual cycle	0.172	0.057	8.918	0.003	1.187	1.061	1.329
Duration of infertility	0.056	0.047	1.390	0.238	1.057	0.964	1.159
AFC	0.641	0.070	84.345	<0.001	1.898	1.655	2.176
LH at MC3	0.010	0.025	0.167	0.683	1.010	0.962	1.061
E2 at MC3	-0.002	0.004	0.367	0.545	0.998	0.991	1.005
P at MC3	0.143	0.121	1.389	0.238	1.154	0.909	1.464
FSH at MC3	-0.151	0.067	5.139	0.023	0.859	0.754	0.980
AMH at MC3	1.207	0.128	89.114	<0.001	3.345	2.603	4.298
Endometrial thickness at MC3	0.042	0.052	0.637	0.425	1.043	0.941	1.155
Dosing days of Gn	0.036	0.042	0.729	0.393	1.036	0.955	1.125
Initial dose of Gn	-0.006	0.002	8.675	0.003	0.994	0.990	0.998
Total dose of Gn	-0.000	0.000	4.513	0.034	1.000	0.999	1.000
Endometrial thickness on HCG day	0.079	0.048	2.774	0.096	1.083	0.986	1.189
LH on HCG day	-0.199	0.077	6.743	0.009	0.820	0.705	0.952
E2 on HCG day	0.001	0.000	56.290	<0.001	1.001	1.000	1.001
P on HCG day	0.679	0.197	11.898	<0.001	1.971	1.340	2.898
FSH on HCG day	0.018	0.019	0.911	0.340	1.018	0.981	1.057

BMI: body mass index; AFC: antral follicle count; MC3: menstrual cycle day 3; LH: luteinizing hormone; E2: estradiol; P: progesterone; FSH: follicle-stimulating hormone; AMH: anti-Müllerian hormone; HCG: human chorionic gonadotropin; Gn: gonadotropin; S.E: standard error; OR: odds ratio; CI: confidence interval.