Review Article

Deep Learning in Cancer Diagnosis and Prognosis Prediction: A Minireview on Challenges, Recent Trends, and Future Directions

Table 3

Summary of the studies for the segmentation/detection of cancers.

PublicationType(s) of cancerType of dataMethodsPerformance

[66]Breast cancerUltrasound images, 2 datasets (A & B)LeNet, U-Net, AlexNet (on dataset A) and (on dataset B)
[67]Breast lesionsTwo custom datasetsFCN-AlexNet, FCN-32s, FCN-16s, and FCN-8sDice score of 0.7626 (FCN-16s)
[68]Breast cancerCamelyon16DL algorithmSlide-level AUC of 99%
[69]Breast cancerInternational Conference on Pattern Recognition 2012, MITOS-ATYPIA-14, Tumor Proliferation Assessment Challenge 2016Faster region CNN, ResNET-50, DenseNet-2010.691 -measure for the MITOS-ATYPIA-14 dataset
[70]MultipleCustom histopathology image datasetMultilayer perceptron, logistic modal tree, sequential minimal optimization, Naïve Bayes, random forest, rotation forest, J-Rip, and PART algorithmsRotation forest algorithm achieved an accuracy of 85.7% for binary classification between cancerous and noncancerous cells
[71]Breast cancerICPR 2014 mitosis dataset, TUPAC 2016 mitotic cell datasetModified regional CNN, , on TUPAC 2016 dataset
[72]Breast cancerCustom dynamic contrast-enhanced MRI dataset3D deep CNN architecture83.7% accuracy, 90.8% sensitivity, 69.3% specificity, AUC of 0.859, overall dice distance of
[73]Breast cancerINbreast databaseDifferent DL methodsAccuracy of 98.96%, MCC of 97.62%, -score of 99.24%, Jaccard similarity coefficient of 86.37%
[74]Lung nodulesLUNA16, LIDC-IDRITwo deep 3D customized mixed link network encoder-decoder architecturesAccuracy of 94.17%
[75]Lung cancerLIDC-IDRI dataset, Kaggle data science bowl challenge dataset3D CNN architecturesDice coefficient for LIDC-IDRI of 0.40, with 0.25 precision and 0.93 recall
[76]Bladder cancerCustom datasetsDL algorithmPer-frame sensitivity and specificity were 90.9% and 98.6%
[77]Full bodyPET imagesDL-based approachDice score of
[78]Brain metastasesCustom MRI datasetDL-based approach (faster region-based CNN model)96% sensitivity,
[79]Thyroid nodulesTwo custom datasets of ultrasound imagesYou only look once v3 dense multireceptive field CNN and 95.23
[80]Liver cancer225 CT scans of hemangioma, hepatocellular carcinoma, and metastatic carcinomaWatershed segmentation, Gaussian mixture model (GMM), and deep neural networkDice score of 0.9743, accuracy of 99.38%
[81]Liver cancerKMC liver dataset, multiorgan Kumar datasetDL model combining residual block, bottleneck block, and attention decoderJaccard index of 0.7206 on KMC liver dataset and 0.6888 on Kumar dataset
[82]Colorectal cancerMICCAI gland segmentation dataset, colorectal adenocarcinoma gland datasetModified U-Net-based architectureDice score of 0.929 on MICCAI gland segmentation dataset, 0.89 on the colorectal adenocarcinoma gland dataset
[83]Colorectal cancerCustom dataset of MRI images of 28 adenocarcinomas and 5 mucinous carcinomasCNN architecture which is a combination of three CNN architecturesDice score of 0.60, precision of 0.76, and recall of 0.55
[84]Ovarian cancerCustom dataset of 127 patients and a total of 469 imagesU-Net modelsDice score of 0.87, an average Pearson correlation of 0.90, and an average intraclass correlation of 0.89
[85]Gastric cancerCustom dataset of 1208 healthy and 533 endoscopic imagesMask R-CNN algorithmAverage dice index of 71%
[86]Gastric cancerCustom dataset of 1340 pathological slicesDeeplab v3+Dice score of 0.9166
[87]Prostate cancerMRI images from an online databaseDL system combining four U-Net modelsOverall average accuracy of 95.3%
[88]Prostate cancerCustom dataset of 1200 ultrasound imagesDL method integrating mask R-CNN and Inception version 3 modelsDice score of 0.88, a precision of 76% on malignant and 75% on benign classes for the classification task using an Inception v3 architecture
[89]Prostate cancerCustom dataset of CT images of 556 cases2D U-Net modelDice score of 0.85, 0.94, and 0.85 for prostate, bladder, and rectum, respectively
[90]Pancreatic cancerCustom dataset of T1w MRI images of 40 subjectsCNN architectureDice score of 0.73
[91]Pancreatic cancerCustom dataset of MRI images belonging to 73 patientsDL method using spiral transformationDice score of