Research Article

[Retracted] Breast Cancer Cells Metastasize to the Tissue-Engineered Premetastatic Niche by Using an Osteoid-Formed Polycaprolactone/Nanohydroxyapatite Scaffold

Figure 6

The migration number of breast cancer cells to the BPMN supernatants coincided with the maturity of the BPMNs. The number of metastatic cells was significantly increased by the BPMNs compared to the control groups (without coculture system treatment). Note that, MDA-MB-231 breast cancer cells appeared to be more responsive to the induced migration compared to MDA-MB-453 and MCF-7 cancer cells. Data are presented as the (). and . BPMNs: bony premetastatic niches.