Computational and Mathematical Methods in Medicine

Research Article

An Efficient Algorithm for the Detection of Outliers in Mislabeled Omics Data

Table 4

Forty-seven misclassified observations detected using MTL-EN for the TNBC dataset#.
IDESRPGRHER2HER2_levelHER2_statusHER2_FISHPerres
TCGA-E9-A22G0.44 (-)0.02 (-)15.32+Non-TNBC32.54
TCGA-A2-A3Y02.18 (+)0.03 (-)11.341+-Non-TNBC29.71
TCGA-A2-A04U0.02 (-)0.02 (-)9.641+-+Non-TNBC22.86
TCGA-BH-A1EW29.98 (-)18.90 (-)42.47-TNBC18.89
TCGA-GM-A2DI23.49 (-)12.05 (-)20.30-TNBC14.73
TCGA-S3-AA0Z16.67 (+)0.07 (+)33.071+Equiv-Non-TNBC14.58
TCGA-AN-A0FJ0.08 (+)0.04 (-)14.281++Non-TNBC14.03
TCGA-BH-A5IZ5.12 (+)0.03 (-)28.08--Non-TNBC13.87
TCGA-OL-A5S00.09 (+)0.06 (-)31.92+Non-TNBC13.45
TCGA-E9-A1ND1.44 (-)0.05 (-)13.05+Non-TNBC13.05
TCGA-B6-A0IJ1.18 (+)0.46 (+)11.12Non-TNBC11.92
TCGA-AR-A2511.57 (+)0.10 (-)14.022+Equiv-Non-TNBC10.70
TCGA-D8-A1JM5.00 (+)0.01 (-)21.851+-Non-TNBC10.52
TCGA-E2-A1II0.14 (-)0.19 (+)10.731+-Non-TNBC10.51
TCGA-A2-A1G623.90 (-)21.45 (-)29.741+-TNBC9.62
TCGA-A2-A0YJ0.09 (+)0.03 (-)240.240-Non-TNBC9.52
TCGA-LL-A5YP0.16 (+)0.05 (-)15.101+-+Non-TNBC9.23
TCGA-E9-A1NC0.11 (-)0.07 (+)15.91+Non-TNBC8.98
TCGA-AC-A62X0.19 (+)0.02 (-)28.53Non-TNBC8.93
TCGA-A7-A13E0.82 (+)0.06 (-)46.082+Equiv-Non-TNBC8.77
TCGA-C8-A3M74.27 (-)0.76 (-)25.47-TNBC8.71
TCGA-AR-A1AJ1.47 (+)0.07 (-)9.74-Non-TNBC8.53
TCGA-BH-A0DL6.99 (+)0.04 (-)9.92-Non-TNBC7.85
TCGA-E2-A1L729.61 (-)22.98 (-)10.33-TNBC7.35
TCGA-AR-A1AH0.03 (+)0.03 (-)34.12-Non-TNBC7.31
TCGA-E2-A14Y0.67 (+)0.03 (+)487.902+Equiv+Non-TNBC7.11
TCGA-LL-A8F51.08 (+)0.04 (-)11.861+-Non-TNBC6.96
TCGA-OL-A97C16.25 (-)8.56 (-)24.04-TNBC6.86
TCGA-A7-A13D0.52 (-)0.81 (+)42.282+Equiv-Non-TNBC6.73
TCGA-AR-A0TP0.04 (+)0.03 (-)13.39-Non-TNBC6.53
TCGA-LL-A6FR0.33 (-)0.04 (+)32.132+Equiv+Non-TNBC6.19
TCGA-A2-A25F0.62 (-)0.23 (+)5.19-Non-TNBC5.86
TCGA-AO-A0JL0.63 (-)0.08 (-)63.601+-+Non-TNBC5.45
TCGA-A2-A1G10.53 (-)0.17 (-)819.762+Equiv+Non-TNBC5.28
TCGA-BH-A42U9.19 (-)1.83 (-)38.37-TNBC4.99
TCGA-AN-A0FX1.13 (-)0.64 (-)24.021++Non-TNBC4.75
TCGA-D8-A1XW0.32 (-)0.11 (+)21.031+-Non-TNBC4.57
TCGA-AR-A24Q1.00 (+)0.36 (-)20.67-Non-TNBC4.52
TCGA-A1-A0SB3.16 (+)0.03 (-)32.35-Non-TNBC4.47
TCGA-A2-A4RX0.68 (+)0.93 (+)26.641+-Non-TNBC3.18
TCGA-AN-A0FL0.09 (-)1.07 (-)15.071++Non-TNBC3.01
TCGA-A2-A0EQ2.13 (-)0.04 (-)30.153++-TNBC2.63
TCGA-EW-A1OV0.23 (-)0.03 (-)28.91--TNBC1.83
TCGA-OL-A5D60.35 (-)0.20 (-)72.13-TNBC1.69
TCGA-C8-A26X0.42 (-)0.13 (-)60.121+-TNBC1.62
TCGA-LL-A7400.30 (-)0.12 (-)68.562+Equiv-TNBC1.48
TCGA-BH-A6R90.59 (-)0.25 (+)8.18-Non-TNBC0.99
#Including the expression values, IHC, and FISH tests of ER, PR, and HER2 (individuals highlighted in bold are suspect individuals). Outliers detected by MTL-EN but not by enetLTS. Perres: the abstract value of Pearson residual.