Research Article
[Retracted] CY-09 Inhibits NLRP3 Inflammasome Activation to Relieve Pain via TRPA1
Figure 5
Effects of AITC (TRPA1 agonists) on cytokine production, intracellular Ca2+ concentration, and NLRP3 activity. (a, b) Effects of AITC on Ca2+ concentration and the expression of TRPA1. Mice were treated with AITC (TRPA1 agonists) as described in Figure 4. (c) Intracellular IL-6, TNF-α, and IL-1β expression level in different groups was detected and statistically analyzed. (d) The expression of NLRP3, ASC, and caspase-1 in footpad tissues of different groups was measured and analyzed. , , and . Data showed .
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