Research Article

[Retracted] Changes of Entropy Index and Cerebral Oxygen Metabolism in the Maintenance of Remifentanil Anesthesia and Their Predictive Value for Postoperative Hyperalgesia

Table 2

The incidence of postoperative hyperalgesia in different patients was (%).

FactorExample number ()Hyperalgesia ()

Age (years)
 <16123 (25.00)4.7900.091
 16~6017921 (11.73)
 >607516 (21.33)
Sexuality
 Man14621 (14.38)0.1080.742
 Woman12019 (15.83)
Body mass index (kg/m2)
 <2410417 (16.35)0.2290.632
 ≥2416223 (14.20)
Degree of education
Junior high school and below10115 (14.85)0.0060.997
High school or technical secondary school9314 (15.05)
College degree or above7211 (15.28)
A history of smoking
 Yes479 (19.15)0.7550.385
 No21931 (14.16)
History of alcohol abuse
 Yes254 (16.00)0.0230.879
 No24136 (14.94)
Long sleep disturbance before surgery
 Yes15830 (18.98)4.7520.029
 No10810 (9.26)
The way of anesthesia maintenance
Thoracic cannula for general anesthesia12820 (15.63)0.1960.907
Static composite anesthesia324 (12.50)
All by intravenous anesthesia10616 (15.09)
ASA classification
 I level12918 (13.95)0.4040.817
 II level11618 (15.52)
 III level214 (19.05)
Operation time (h)
 <219824 (12.12)5.1560.023
 ≥26816 (23.53)
Operative site
 Body surface14222 (15.49)0.1190.989
 Arms and legs558 (14.55)
 Body cavity446 (13.64)
 Other254 (16.00)
The dosage of remifentanil (μg/kg)
 <3018121 (11.60)5.2320.022
 ≥308519 (22.35)
State entropy
Low levels before the induction of anesthesia13018 (13.85)0.2830.595
High levels before the induction of anesthesia13622 (16.18)
Low intraoperative level of 30 min12812 (9.38)6.1920.013
High intraoperative level of 30 min13828 (20.29)
Low levels at the end of the surgery13514 (10.37)4.6740.031
High level at the end of the surgery13126 (19.85)
Reaction entropy
Low levels before the induction of anesthesia13217 (12.88)0.9560.328
High levels before the induction of anesthesia13423 (17.16)
Low intraoperative level of 30 min13314 (10.53)4.2370.040
High intraoperative level of 30 min13326 (19.55)
Low levels at the end of the surgery13513 (9.63)6.2750.012
High level at the end of the surgery13127 (20.61)
Da-jvO2 (ml/l)
Low levels before the induction of anesthesia13418 (13.43)0.5440.461
High levels before the induction of anesthesia13222 (16.67)
Low intraoperative level of 30 min13027 (20.77)6.5380.011
High intraoperative level of 30 min13613 (9.56)
Low levels at the end of the surgery13329 (21.80)9.5340.002
High level at the end of the surgery13311 (8.27)
CERO2 (%)
Low levels before the induction of anesthesia13118 (13.74)0.3400.560
High levels before the induction of anesthesia13522 (16.30)
Low intraoperative level of 30 min12911 (8.53)8.3090.004
High intraoperative level of 30 min13729 (21.17)
Low levels at the end of the surgery13414 (10.45)4.4530.035
High level at the end of the surgery13226 (19.70)

Note: state entropy, reaction entropy, Da-jvO2, and CERO2 are bounded by the mean value, ≤mean value is low level, >mean value is high level; “-” means that there is at least one lattice theoretical number , and there is no value.