In Silico Evaluation of Nonsynonymous SNPs in Human ADAM33: The Most Common Form of Genetic Association to Asthma Susceptibility

Table 1

Unanimous prediction of deleterious missense SNPs in the ADAM33 protein by different online software.

SNP ID	AAS	SIFT	PolyPhen-2	PANTHER-PSEP	SNPs&GO	PROVEAN	GVGD	PredictSNP
rs773091023	P678L	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs764301730	C671R	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs751597707	C669G	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs368984072	G661R	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs777553708	C637Y	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs1334863089	C631F	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs754867141	C606S	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs754867141	C606Y	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs915448220	C573Y	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs1432549895	C519R	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs1262246273	Y513C	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs1203116461	P496L	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs757567846	D483A	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs1424975479	C482F	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs1165412077	C482S	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs779669835	R476C	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs748720838	C475G	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs528261077	G472V	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs1378161696	C463Y	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs768654352	G460R	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs1192357091	C444S	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs1192357091	C444Y	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs777252478	C439Y	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs1321728445	C431S	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs747255442	G428C	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs776082098	C420Y	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs751613984	C388Y	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs1313175203	C371Y	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs764090883	C371R	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs1297854732	C360R	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease
rs1351880201	D219V	Deleterious	Probably damaging	Probably damaging	Disease	Deleterious	C65	Disease