Potential Diagnostic and Prognostic Values of CBX8 Expression in Liver Hepatocellular Carcinoma, Kidney Renal Clear Cell Carcinoma, and Ovarian Cancer: A Study Based on TCGA Data Mining

Table 4

Univariate and multivariate analyses of different parameters for overall survival, relapse-free survival, and disease-free survival in LIHC patients.

Carcinoma	Survival	Characteristics	Univariate analysis			Multivariate analysis
				HR	95% CI		HR	95% CI
LIHC	OS	CBX8 expression high vs. low	<0.001	2.6	1.7-3.8	<0.001	2.5	1.7-3.9
		Gender male vs. female	0.26	0.81	0.57-1.2
		Age, years ≥60 vs. <60	0.27	1.2	0.86-1.7
		TNM stage III/IV vs. I/II	<0.001	2.4	1.7-3.5	<0.001	2.4	1.7-3.5
		Grade G3/G4 vs. G1/G2	0.54	1.1	0.78-1.6
	RFS	CBX8 expression high vs. low	0.028	1.4	1-1.9	0.086	1.3	0.96-1.8
		Gender male vs. female	0.94	0.99	0.72-1.4
		Age, years ≥60 vs. <60	0.75	1	0.78-1.4
		TNM stage III/IV vs. I/II	<0.001	2.4	1.7-3.3	<0.001	2.3	1.7-3.2
		Grade G3/G4 vs. G1/G2	0.52	1.1	0.81-1.5
	DFS	CBX8 expression high vs. low	<0.001	1.9	1.4-2.6	<0.001	1.9	1.4-2.6
		Gender male vs. female	0.42	0.89	0.68-1.2
		Age, years ≥60 vs. <60	0.37	1.1	0.86-1.5
		TNM stage III/IV vs. I/II	<0.001	2.1	1.6-2.8	<0.001	2.1	1.6-2.8
		Grade G3/G4 vs. G1/G2	0.63	1.1	0.81-1.4