[Retracted] HMGB3 Targeted by miR-145-5p Impacts Proliferation, Migration, Invasion, and Apoptosis of Breast Cancer Cells

Figure 1

HMGB3 expression is substantially high in BC cells. (a) Boxplot of HMGB3 expression in healthy breast tissues and BC tissues (comparison between two groups: ). (b) Survival analysis of HMGB3 expression on BC patient’s prognosis (comparison between two groups: ). (c) Correlation between HMGB3 and BC clinical features (T stage, N stage, asterisk indicates statistically significant differences, and ). (d) Relationship between HMGB3 expression and BC subtypes (asterisk indicates statistically significant differences and ). (e, f) HMGB3 mRNA and protein levels in human breast epithelial cell line MCF-10A and BC cell lines MDA-MB-468, MDA-MB-231, T47D, and ZR-75-30. Results were presented as . Log-rank test was utilized for survival analysis. Correlation between HMGB3 and clinical features with different subtypes of BC was analyzed by the Kruskal-Wallis test. The others were statistically analyzed by Student’s -test. Samples in each group were plated in triplicate. .

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