Computational and Mathematical Methods in Medicine

Research Article

[Retracted] The Efficacy of Glucocorticoids in the Treatment of Nonarteritic Anterior Ischemic Optic Neuropathy: A Systematic Review and Meta-Analysis

Table 1

Characteristics of the eligible studies.
StudyStudy
design		CountryTreatmentNo. of patientsGender (M/F)AgeFollow-upDuration
InterventionControlInterventionControlInterventionControlInterventionControl
Kaderli 2007 [21]Retrospective cohort studyTurkeyTriamcinolone intravitreal injection of 4 mg/0.1 mLNo treatment462/23/356-7456-74>9 monthsJune 2004 to January 2005
Hayreh 2008 [20]Retrospective cohort studyUSPrednisone 80 mg daily for 2 weeks, and then tapered down to 70 mg for 5 days, 60 mg for 5 days, and then cutting down by 5 mg every 5 daysNo treatment312301188/124175/1263 months1973 to 2000
Rebolleda 2012Retrospective cohort studySpainPrednisone 80 mg daily for 2 weeks, and then tapered down to 70 mg for 5 days, 60 mg for 5 days, and then cutting down by 5 mg every 5 daysNo treatment10277/314/136 monthsSeptember 2008 to September 2009
Kinori 2014 [22]Retrospective cohort studyIsraelMethylprednisolone (1 g/day) for 3 days, followed by oral prednisone (1 mg/kg) for 11 daysNo treatment242414/1016/86 months—
Radoi 2014 [25]Retrospective cohort studyFranceTriamcinolone intravitreal injection of 4 mg/0.1 mLNo treatment2115NRNR59-9159-916 monthsFebruary 2009 to November 2012
Pakravan 2016 [23]Randomized controlled trialIranMethylprednisolone 500 mg twice a day for 3 days, followed by 2 weeks of oral prednisolone 1 mg/kg/dayPlacebo303020/721/96 monthsDecember 2010 to November 2013
Pakravan 2017 [24]Prospective cohort studyIranMethylprednisolone 500 mg twice a day for 3 days followed with oral prednisolone 1 mg/kg for 10 daysSuggested treatments433032/1121/96 monthsMay 2012 to October 2015
Saxena 2018 [27]Randomized controlled trialIndiaPrednisone 80 mg daily for 2 weeks, and then tapered down to 70 mg for 5 days, 60 mg for 5 days, and then cutting down by 5 mg every 5 daysPlacebo191913/611/86 monthsMarch 2015 to August 2016
Durbant 2021 [19]Retrospective cohort studyFranceTriamcinolone intravitreal injection of 4 mg/0.1 mLNo treatment4127——66686 months2009 to 2017