The Clinical Application Value of the Prognostic Nutritional Index for the Overall Survival Prognosis of Patients with Esophageal Cancer: A Robust Real-World Observational Study in China

Table 1

Patients’ characteristics in the training cohort.

Variables	Overall (%)	PNI		value
		High risk ()	Low risk ()
	1332	490	842
Age				<0.001
≤60	548 (41.1)	160 (32.7)	388 (46.1)
>60	784 (58.9)	330 (67.3)	454 (53.9)
Postoperative adjuvant treatment				0.003
No	720 (54.1)	291 (59.4)	429 (51.0)
Yes	612 (45.9)	199 (40.6)	413 (49.0)
Gender				<0.001
Female	244 (18.3)	65 (13.3)	179 (21.3)
Male	1088 (81.7)	425 (86.7)	663 (78.7)
KPS score				1
≥80	1327 (99.6)	488 (99.6)	839 (99.6)
≤70	5 (0.4)	2 (0.4)	3 (0.4)
Tumor size				<0.001
<5 cm	900 (67.6)	298 (60.8)	602 (28.5)
≥5 cm	432 (32.4)	192 (39.2)	602 (28.5)
Tumor grade				0.963
Well differentiated	251 (18.8)	93 (19.0)	158 (18.8)
Moderate differentiated	521 (39.1)	195 (39.8)	326 (38.7)
Poorly differentiated	522 (39.2)	189 (38.6)	333 (39.5)
Other	38 (2.9)	13 (2.7)	25 (3.0)
Tumor location				0.185
Lower chest	293 (22.0)	121 (24.7)	172 (20.4)
Middle chest	712 (53.5)	255 (52.0)	457 (54.3)
Upper chest	327 (24.5)	114 (23.3)	213 (25.3)
T stage				0.295
T0-2	405 (30.4)	140 (28.6)	265 (31.5)
T3-4	927 (69.6)	350 (71.4)	577 (68.5)
N stage				0.865
N0-1	970 (72.8)	355 (72.4)	615 (73.0)
N2-3	362 (27.2)	135 (27.6)	227 (27.0)
M stage				0.784
M0	1331 (99.9)	489 (99.8)	842 (100.0)
M1	1 (0.1)	1 (0.2)	0 (0.0)
TNM stage				0.241
0-II	581 (43.6)	203 (41.4)	378 (44.9)
III-IV	751 (56.4)	287 (58.6)	464 (55.1)