Research Article

The Clinical Application Value of the Prognostic Nutritional Index for the Overall Survival Prognosis of Patients with Esophageal Cancer: A Robust Real-World Observational Study in China

Table 3

Patients’ characteristics in the testing cohort.

VariablesOverall (%)PNI value
High risk ()Low risk ()

1329502827
Age0.003
 ≤60546 (41.1)180 (35.9)366 (44.3)
 >60783 (58.9)322 (64.1)461 (55.7)
Postoperative adjuvant treatment0.016
 No702 (52.8)287 (57.2)415 (50.2)
 Yes627 (47.2)215 (42.8)412 (49.8)
Gender0.015
 Female244 (18.4)75 (14.9)169 (20.4)
 Male1085 (81.6)427 (85.1)658 (79.6)
KPS score1
 ≥801324 (99.6)500 (99.6)824 (99.6)
 ≤705 (0.4)2 (0.4)3 (0.4)
Tumor size0.001
 <5 cm898 (67.6)311 (62.0)587 (71.0)
 ≥5 cm431 (32.4)191 (38.0)240 (29.0)
Tumor grade0.953
 Well differentiated236 (17.8)92 (18.3)144 (17.4)
 Moderate differentiated540 (40.6)205 (40.8)335 (40.5)
 Poorly differentiated516 (38.8)192 (38.2)324 (39.2)
 Other37 (2.8)13 (2.6)24 (2.9)
Tumor location0.846
 Lower chest280 (21.1)105 (20.9)175 (21.2)
 Middle chest706 (53.1)263 (52.4)443 (53.6)
 Upper chest343 (25.8)134 (26.7)209 (25.3)
T stage0.037
 T0-2420 (31.6)141 (28.1)279 (33.7)
 T3-4909 (68.4)361 (71.9)548 (66.3)
N stage0.168
 N0-1993 (74.7)364 (72.5)629 (76.1)
 N2-3336 (25.3)138 (27.5)198 (23.9)
M stage1
 M01325 (99.7)500 (99.6)825 (99.8)
 M14 (0.3)2 (0.4)2 (0.2)
TNM stage0.132
 0-II579 (43.6)205 (40.8)374 (45.2)
 III-IV750 (56.4)297 (59.2)453 (54.8)