Computational and Mathematical Methods in Medicine / 2022 / Article / Tab 4 / Research Article
The Clinical Application Value of the Prognostic Nutritional Index for the Overall Survival Prognosis of Patients with Esophageal Cancer: A Robust Real-World Observational Study in China Table 4 Univariate and multivariate Cox proportional hazards regression analyses of OS in patients of the testing cohort.
Variable Univariate Multivariate HR (95% CI) valueHR (95% CI) valueAge (60/>60) 0.943 (0.801-1.111) 0.483 Postoperative adjuvant treatment (no/yes) 1.004 (0.926-1.088) 0.928 Gender (female/male) 0.74 (0.655-0.836) <0.001 0.677 (0.529-0.866) 0.002 KPS score (≥80/≤70) 1.136 (0.568-2.275) 0.718 Tumor size (<5 cm/≥5 cm) 0.764 (0.705-0.829) <0.001 0.8 (0.674-0.949) 0.01 Tumor grade Well differentiated 1 (reference) 1 (reference) Moderate differentiated 1.475 (1.153-1.886) 0.002 1.232 (0.96-1.581) 0.101 Poorly differentiated 1.565 (1.225-1.997) <0.001 1.428 (1.114-1.831) 0.005 Other 0.314 (0.127-0.773) 0.012 0.567 (0.228-1.407) 0.221 Tumor location Lower chest 1 (reference) Middle chest 1.059 (0.857-1.310) 0.595 Upper chest 1.129 (0.892-1.429) 0.314 T stage (T0-2/T3-4) 0.637 (0.574-0.706) <0.001 0.601 (0.484-0.745) <0.001 N stage (N0-1/N2-3) 0.566 (0.521-0.615) <0.001 0.584 (0.482-0.708) <0.001 M stage (M0/M1) 0.219 (0.133-0.361) <0.001 0.12 (0.044-0.329) <0.001 TNM stage (I-II/III-IV) 0.542 (0.494-0.596) <0.001 0.473 (0.38-0.588) <0.001 PNI (<49/≥49) 1.145 (1.055-1.243) 0.001 1.212 (1.027-1.431) 0.023