Combination of the NRF2 Inhibitor and Autophagy Inhibitor Significantly Inhibited Tumorigenicity of Castration-Resistant Prostate Cancer

Figure 3

NRF2 is suppressed in untreated PCa tissues and is associated with disease progression. (a) The representative images of IHC 0, 1, 2, and 3 of nuclear and cytoplasmic levels of NRF2 in PCa. (b) Higher total, (c) nuclear, and (d) cytoplasm protein levels of NRF2 correlated to longer BCR-free survival time. (e) Taylor dataset analysis showed that NRF2 low expression was correlated to poor outcome in PCa.

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