Combination of the NRF2 Inhibitor and Autophagy Inhibitor Significantly Inhibited Tumorigenicity of Castration-Resistant Prostate Cancer

Figure 5

Combination of the NRF2 inhibitor and autophagy inhibitor significantly inhibited tumorigenicity of PCa cells. (a) The representative images of PCa 22Rv1 spheres after treatment with the NRF2 inhibitor, autophagy inhibitor, and combination. (b) The cell viability, sphere number, and organized size of PCa 22Rv1 spheres after treatment with the NRF2 inhibitor, autophagy inhibitor, and combination. (c) The representative images of PCa DU145 spheres after treatment with the NRF2 inhibitor, autophagy inhibitor, and combination. (d) The cell viability, sphere number, and organized size of PCa DU145 spheres after treatment with the NRF2 inhibitor, autophagy inhibitor, and combination.

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