Characteristics All PNI value<39.7 ≥39.7 Number of patients 940 361 719 Age, years 0.270 Sex, (%) 0.185 Male 424 (45.11) 153 (42.38) 271 (46.80) Female 516 (54.89) 208 (57.62) 308 (53.20) Ethnicity, (%) 0.832 White 669 (71.17) 261 (72.30) 408 (70.47) Black 82 (8.72) 30 (8.31) 52 (8.98) Other 189 (20.11) 70 (19.39) 119 (20.55) Vital signs SBP, mmHg <0.001 DBP, mmHg <0.001 MAP, mmHg <0.001 Heart rate, beats/min <0.001 Temperature, °C <0.001 SpO2, % <0.001 Respiratory rate, t/min <0.001 Comorbidities Heart failure, (%) 106 (11.28) 60 (16.62) 46 (7.94) <0.001 Atrial fibrillation 282 (30.00) 128 (35.46) 154 (26.60) 0.004 CHD, (%) 163 (17.34) 61 (16.90) 102 (17.62) 0.777 Laboratory parameters PNI <0.001 Albumin, g/dl <0.001 WBC, 109 /l 0.284 Platelet, 109 /l <0.001 Lymphocyte, % <0.001 Creatinine, mg/dl <0.001 BUN, mg/dl <0.001 Serum chloride, mg/dl 0.005 Anion gap, mg/dl 0.869 Scoring systems SAPSII score <0.001 SOFA score <0.001 SIRS score <0.001 Clinical outcomes, (%) 30-day mortality 244 (25.96) 114 (31.58) 130 (22.45) <0.001 90-day mortality 244 (25.96) 144 (39.89) 151 (26.08) <0.001 One-year mortality 295 (31.38) 170 (47.09) 179 (30.92) <0.001 Length of stay in ICU <0.001 Length of stay in hospital <0.001