Computational and Mathematical Methods in Medicine

Research Article

Elevated Serum Fibroblast Growth Factor 21 Is Relevant to Heart Failure Patients with Reduced Ejection Fraction

Table 1

The demographic and baseline clinical characteristics of the HFrEF and control groups.
VariablesHFrEF groupControl group value
Gender (male) (, %)86 (67.19%)51 (71.83%)0.527
Age (years)0.077
BMI (kg/m2)0.120
Hypertension ()65290.186
Diabetes mellitus ()30120.365
BNP (ng/L)≤0.001
BUN (mmol/L)0.09
Creatinine (μmol/L)0.002
NYHA class III (%)36 (28.13%)—≤0.001
NYHA class IV (%)92 (71.87%)—≤0.001
LVEDD (mm)≤0.001
LVEF (%)≤0.001
FGF21 (pg/mL)≤0.001
HFrEF: Heart Failure with reduced Ejection Fraction; BMI: body mass index; BNP: brain natriuretic peptide; BUN: blood urea nitrogen; NYHA: New York Heart Association; LVEDD: left ventricular end-diastolic diameter; LVEF: left ventricular ejection fraction; FGF21: fibroblast growth factor 21.