Elevated Serum Fibroblast Growth Factor 21 Is Relevant to Heart Failure Patients with Reduced Ejection Fraction

Table 3

Univariate Cox analysis for prognosis in patients with HFrEF.

Variables	OR value	value	95% CI
Gender (male, )	0.146	≤0.001	0.061-0.345
Age (years)	0.954	0.004	0.923-9.985
BMI (kg/m^2)	0.971	0.522	0.887-1.063
Hypertension ()	2.489	0.007	1.286-4.815
Diabetes mellitus ()	0.602	0.154	0.300-1.210
BNP (ng/L)	1.005	≤0.001	1.003-1.006
Creatinine (μmol/L)	1.003	0.002	1.001-1.005
LVEDD (mm)	0.896	0.026	0.814-0.987
LVEF (%)	≤0.001	0.005	≤0.001-≤0.001
FGF21 (pg/mL)	0.964	0.008	0.939-0.990

BMI: body mass index; BNP: brain natriuretic peptide; LVEDD: left ventricular end-diastolic diameter; LVEF: left ventricular ejection fraction; FGF21: fibroblast growth factor 21.