Pharmacokinetics of Veratramine and Jervine from Alcohol Extracts of Radix Veratri

Table 5

Comparison of main pharmacokinetic parameters of Radix Veratri alcohol extract.

Compound

Group

Gender

(μg/Lh)

AUC0-∞ (μg/Lh)

(h)

MRT0-∞ (h)

(L/kg)

(L/h/kg)

VER

—

♀♂

0.04 g/kg

♀

0.08 g/kg

0.16 g/kg

0.04 g/kg

♂

0.08 g/kg

0.16 g/kg

JER

—

♀♂

0.04 g/kg

♀

0.08 g/kg

0.16 g/kg

0.04 g/kg

♂

0.08 g/kg

0.16 g/kg