[Retracted] The Levels of TNF-α, Tissue Factor, and Coagulation Function in Rats with Pulmonary Hypertension and the Intervention Effect of Sildenafil Encapsulated by Targeted Nanocarriers

Table 2

Intervention effect of targeted nanocarrier encapsulation sildenafil on PAH rats.

Group	Mean pulmonary artery pressure (mmHg)	Pulmonary small blood vessel media thickness (%)	Cardiac cell area (μm^2)	TNF-α (ng/L)	Tissue factor (pg/mL)	Fibrinogen (g/L)
Normal SD rat ()
NS group ()	^a	^a	^a	^a	^a	^a
Sildenafil group ()	^a	^a	^a	^a	^a	^a
TNC-E group ()	^a	^a	^a	^a	^a	^a
CNC-sildenafil group ()	^a	^a	^a	^a	^a	^a
TNC-sildenafil group ()	^b	^b	^b	^b	^b	^b
	65.892	95.046	76.931	42.419	20.970	22.133
	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001

Note: ^a means compared with normal SD rats. ^b means compared with the NS group. NS group: normal saline; sildenafil group: sildenafil; TNC-E group: targeted nanoempty carrier: CNC-sildenafil group: ordinary nanocarrier encapsulated sildenafil; TNC-sildenafil group: targeted nanocarrier encapsulation sildenafil.