Research Article

[Retracted] Renoprotective Effect of Intraoperative Dexmedetomidine in Renal Transplantation

Table 3

Effects of dexmedetomidine on early renal function markers. Dex: group administrated with dexmedetomidine; Con: control group received saline; KIM-1: kidney injury molecule-1; Cr: serum creatinine; VAS: visual analogue scale. Patients who accepted dialysis after operation in the first week were excluded. Data are given as the median (SD). compared between two groups.

DexCon value

KIM-1 (pg/ml)
0 h446.685 (335.46)406.511 (298.79)0.612
2 h322.641 (237.31)481.981 (289.18)0.018
24 h103.931 (89.965)177.828 (139.67)0.013
48 h16.934 (2.653)59.499 (59.957)0.000
72 h17.299 (3.590)41.439 (34.945)0.000
144 h18.841 (4.657)19.778 (2.4495)0.316
Urea (mmol/L)
Before operation25.399 (8.228)24.231 (8.053)0.597
Day 121.412 (6.661)20.138 (5.755)0.403
Day 221.915 (7.892)22.638 (9.110)0.756
Day 324.865 (10.480)24.414 (11.493)0.880
Day 424.919 (12.773)24.541 (13.315)0.915
Day 523.031 (14.156)22.379 (13.087)0.860
Day 620.931 (14.608)19.562 (13.496)0.719
Cr (μmol/L)
Before operation994.004 (330.268)940.538 (284.639)0.522
Day 1689.850 (272.912)675.831 (287.469)0.854
Day 2533.023 (299.396)571.914 (329.329)0.650
Day 3448.458 (332.852)476.707 (354.369)0.763
Day 4380.192 (310.766)412.866 (338.047)0.712
Day 5344.400 (309.069)345.238 (279.700)0.992
Day 6310.204 (278.493)306.300 (269.450)0.958
Urine output (ml)
Day 12807.879 (1473.658)2593.750 (913.461)0.486
Day 22572.121 (693.311)2568.438 (703.512)0.983
Day 32497.273 (740.364)2543.438 (681.718)0.795
Day 42451.515 (617.293)2570.938 (923.183)0.541
Day 52379.394 (583.095)2344.688 (474.885)0.794
Day 62415.758 (538.372)2350.313 (594.673)0.643
VAS
3 h3.000 (1.458)3.781 (1.845)0.070
6 h2.939 (1.478)3.937 (1.664)0.010
12 h2.455 (1.301)3.625 (1.601)0.002
24 h1.333 (0.854)1.719 (0.958)0.067
48 h0.424 (0.614)0.563 (0.564)0.245