Exploring Myocardial Ischemia-Reperfusion Injury Mechanism of Cinnamon by Network Pharmacology, Molecular Docking, and Experiment Validation

Figure 7

Taxifolin alleviated hypoxia/reoxygenation-induced cardiac dysfunction. Hypoxia/reoxygenation increased cardiac contractility dysfunction; however, it was reversed by taxifolin derived from cinnamon. Representative images of cardiac fluorescence imaging (a), quantification of FAC (b), SA (c), DA (d) in zebrafish larvae treated with hypoxia for 48 hours/reoxygenation for 2 hours (pretreated with PBS, 1% DMSO solvent, taxifolin, eugenol, oleic acid, and cinnamaldehyde, respectively) or normoxic water starting at 2 dpf. . , , .

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