Research Article

Upregulation of NDUFAF2 in Lung Adenocarcinoma Is a Novel Independent Prognostic Biomarker

Table 1

Correlation between NDUFAF2 expression and baseline clinicopathologic characteristics of LUAD patients from the TCGA database.

CharacteristicLow expression of NDUFAF2High expression of NDUFAF2

256257
Age, (%)0.928
 ≤65125 (24.3%)123 (23.9%)
 >65131 (25.7%)134 (26.1%)
Gender, (%)0.892
 Female139 (27.1%)137 (26.7%)
 Male117 (22.8%)120 (23.4%)
Pathologic stage, (%)<0.001
 Stage I156 (30.9%)118 (23.4%)
 Stage II57 (11.3%)64 (12.7%)
 Stage III26 (5.1%)58 (11.5%)
 Stage IV13 (2.6%)13 (2.6%)
T stage, (%)0.002
 T1102 (20%)66 (12.9%)
 T2121 (23.7%)155 (30.4%)
 T324 (4.7%)23 (4.5%)
 T46 (1.2%)13 (2.5%)
N stage, (%)<0.001
 N0184 (36.7%)146 (29.1%)
 N138 (7.6%)57 (11.4%)
 N224 (4.8%)50 (10%)
 N31 (0.2%)1 (0.2%)
M stage, (%)1.000
 M0165 (44.7%)179 (48.5%)
 M112 (3.3%)13 (3.5%)
Smoker, (%)0.160
 No31 (6.2%)43 (8.6%)
 Yes219 (43.9%)206 (41.3%)
OS event, (%)0.001
 Alive181 (35.3%)145 (28.3%)
 Dead75 (14.6%)112 (21.8%)
Age, median (IQR)66 (59, 73)66 (59, 72)0.652