Expression Profiles of Long Noncoding RNAs and Messenger RNAs in a Rat Model of Spinal Cord Injury

Figure 4

lncRNA-mRNA coexpression network in SCI of rat model. Coexpression circos map: the outermost circle is the autosome distribution diagram of this species; the second and third circles are the distribution of DE genes on chromosomes. The red line indicates that genes are upregulated, and the green line indicates that genes are downregulated. The higher the column, the more DE genes there are. In the fourth and fifth circles, DE lncRNAs were shown in the same form as genes. The corresponding relationship between top 500 coexpressed key lncRNAs and genes is indicated by the internal line (a). The GO enrichment results of key lncRNA coexpressed DE mRNAs correspond to the top 10 terms (b). The KEGG enrichment results of total key lncRNA coexpressed DE mRNAs correspond to the top 10 terms (c). The axis represents the enrichment score. More differential genes are present in items with larger bubbles. Bubble color changes from gray to red, with a gradually decreasing enrichment value, indicating increasing significance.

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