Computational and Mathematical Methods in Medicine

Immune System Modeling and Related Pathologies


Publishing date
02 Nov 2012
Status
Published
Submission deadline
15 Jun 2012

1Department of Pharmaceutical Sciences, University of Catania, Catania, Italy

2Cancer Vaccine Center, Dana-Farber Cancer Institute, Boston, MA, USA

3Algorithmic Bioinformatics, Bonn-Aachen International Center for Information Technology (B-IT), University of Bonn, Dahlmannstraße 2, Bonn, Germany


Immune System Modeling and Related Pathologies

Description

Revolutions in biotechnology and information technology have produced enormous amounts of data and are accelerating the extension of our knowledge of biological systems. These advances are changing the way biomedical research, development, and applications are done. Clinical data complement biological data, enabling detailed descriptions of various healthy and diseased states, progression and responses to therapies. The availability of data representing various biological states, processes, and their time dependencies enables the study of biological systems at various levels of organization, from molecule to organism, and even population levels. Multiple sources of data support a rapidly growing body of biomedical knowledge; however our ability to analyze and interpret these data lags far behind data generation and storage capacity. Mathematical and computational models are increasingly used to help interpret biomedical data produced by high-throughput genomics and proteomics projects. Advanced applications of computer models that enable the simulation of biological processes are used to generate hypotheses and plan experiments. Appropriately interfaced with biomedical databases, computational models are necessary for rapid access to and sharing of knowledge through data mining and knowledge discovery approaches.

We particularly take an interest in manuscripts that investigate the physiology and pathology of the immune responses, from cellular and/or molecular point of views. Applications of computational simulations, mathematical and statistical methods to the discovery, design, and optimization of drugs, vaccines, and other immunotherapies, as well as reviews, are also welcome. Potential topics include, but are not limited to:

  • Modeling of cancer and immune system competition
  • Modeling of autoimmune diseases
  • Cellular and molecular modeling of specific aspects of the immune system
  • Modeling of immune response to infectious diseases
  • Modeling and optimization of novel treatments against diseases (including pharmacogenomics)

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/cmmm/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 274702
  • - Editorial

Immune System Modeling and Related Pathologies

Francesco Pappalardo | Vladimir Brusic | Holger Fröhlich
  • Special Issue
  • - Volume 2012
  • - Article ID 790482
  • - Research Article

Modeling Innate Immune Response to Early Mycobacterium Infection

Rafael V. Carvalho | Jetty Kleijn | ... | Fons J. Verbeek
  • Special Issue
  • - Volume 2012
  • - Article ID 736394
  • - Research Article

Computational Modeling of Microabscess Formation

Alexandre Bittencourt Pigozzo | Gilson Costa Macedo | ... | Marcelo Lobosco
  • Special Issue
  • - Volume 2012
  • - Article ID 342602
  • - Research Article

Time-Course Analysis of Main Markers of Primary Infection in Cats with the Feline Immunodeficiency Virus

B. Ribba | H. El Garch | ... | P. Vanhems
  • Special Issue
  • - Volume 2012
  • - Article ID 173521
  • - Research Article

Relaxation Estimation of RMSD in Molecular Dynamics Immunosimulations

Wolfgang Schreiner | Rudolf Karch | ... | Nevena Ilieva
  • Special Issue
  • - Volume 2012
  • - Article ID 842329
  • - Research Article

How the Interval between Prime and Boost Injection Affects the Immune Response in a Computational Model of the Immune System

F. Castiglione | F. Mantile | ... | A. Prisco
  • Special Issue
  • - Volume 2012
  • - Article ID 676015
  • - Review Article

Understanding Immunology via Engineering Design: The Role of Mathematical Prototyping

David J. Klinke | Qing Wang
  • Special Issue
  • - Volume 2012
  • - Article ID 850754
  • - Research Article

A Mathematical Model of Immune-System-Melanoma Competition

Marzio Pennisi
Computational and Mathematical Methods in Medicine
 Journal metrics
Acceptance rate38%
Submission to final decision61 days
Acceptance to publication39 days
CiteScore1.840
Impact Factor1.563
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