New Perspectives for Computer-Aided Discrimination of Parkinson’s Disease and Essential Tremor

Figure 4

Neural drive to left and right wrist flexors and extensors in representative PD patient during arms outstretched task. (a) Neural drive as estimated by low-pass filtering of cumulative motor unit spike train. Left wrist extensors and flexors exhibit voluntary drive; right wrist extensors and flexors exhibit tremulous drive; (b) cross-correlations (CC) of neural drives; EXT L: left wrist extensors, FLE L: left wrist flexors, EXT R: right wrist extensors, and FLE R: right wrist flexors. The -axis denotes the correlation lag in seconds.

(a)

(b)