Modeling of Tumor Growth Incorporating the Effects of Necrosis and the Effect of Bevacizumab

Table 1

The parameters of the extended tumor growth model and their values after the identification.

Parameter	Parameter name	Value	Dimension
	Tumor growth rate	0.4579
	Inhibition rate	0.1685
	Clearance	0.1825
	Necrosis rate	0.1030
	Modified inhibition rate		mg/(ml⋅day)
	Initial proliferating tumor volume	49.0497
	Michaelis-Menten constant of the inhibitor	0.4409
	Median effective dose of the inhibitor