Selective Phenome Growth Adapted Model: A Novel Landscape to Represent Aptamer Ligand Binding

Figure 3

Comparison of basins: the accessibility of local optima discovered by 100,000 independent adaptive walks on four types of landscape, shown in blue. (a) The random landscape, 99249 unique optima. (b) The random landscape, 100,000 unique optima. (c) The Genome selected landscape, 99381 unique optima. (d) Phenome selected landscape, 98977 unique optima. The log scale panel shows the same phenome selected landscape data in black. Red horizontal lines show mean and grey horizontal lines show one standard deviation from the mean.

(a) Random

(b) Random

(c) Genome selected growth

(d) Phenome selected growth