Research Article

Sparse Learning of the Disease Severity Score for High-Dimensional Data

Table 5

PANTHER overrepresentation analysis results. No.: number of associated genes; Exp.: expected number of genes by chance; Fold: number of times enriched.

GO biological process complete GOID No. Exp. Fold value

Defense response to virus(GO:0051607)18.6229.21
Response to virus(GO:0009615)20.9620.75
Type I interferon signaling pathway(GO:0060337)14.2849.54
Cellular response to type I interferon(GO:0071357)14.2849.54
Response to type I interferon(GO:0034340)14.2947.96
Immune response(GO:0006955)325.425.91
Immune system process(GO:0002376)358.204.27
Innate immune response(GO:0045087)263.796.87
Defense response(GO:0006952)316.125.07
Defense response to other organisms(GO:0098542)191.7310.97
Immune effector process(GO:0002252)191.7510.85
Cytokine-mediated signaling pathway(GO:0019221)202.139.40
Cellular response to cytokine stimulus(GO:0071345)212.727.72
Response to cytokine(GO:0034097)223.166.96
Response to other organisms(GO:0051707)223.236.81
Response to external biotic stimulus(GO:0043207)223.236.81
Response to biotic stimulus(GO:0009607)223.316.65
Negative regulation of viral genome replication(GO:0045071)8.1941.11
Negative regulation of viral process(GO:0048525)9.3624.90
Regulation of viral genome replication(GO:0045069)8.3026.56
Negative regulation of viral life cycle(GO:1903901)8.3523.02
Response to stress(GO:0006950)3414.202.40
Negative regulation of multiorganism process(GO:0043901)9.6015.06
Response to external stimulus(GO:0009605)268.483.06
Cellular response to interferon-gamma(GO:0071346)8.5016.14
Regulation of viral process(GO:0050792)9.7911.43
Response to interferon-gamma(GO:0034341)8.5713.93
Regulation of symbiosis(GO:0043903)9.8810.17
Regulation of viral life cycle(GO:1903900)8.7410.86
Interferon-gamma-mediated signaling pathway(GO:0060333)6.3119.33
Response to stimulus(GO:0050896)4326.531.62
Regulation of defense response(GO:0031347)143.034.61
Regulation of cytokine production(GO:0001817)122.195.48
Cellular response to organic substance(GO:0071310)238.362.75
Regulation of multiorganism process(GO:0043900)111.816.07
Response to interferon-alpha(GO:0035455)4.0945.44
Cellular response to chemical stimulus(GO:0070887)2510.062.49
Cell surface receptor signaling pathway(GO:0007166)239.042.54
Multiorganism process(GO:0051704)228.402.62