Research Article

Neural Network-Based State Estimation for a Closed-Loop Control Strategy Applied to a Fed-Batch Bioreactor

Table 1

Performance evaluation of the RBF neural network.

Test

Normal operating conditions1.58 × 10−62.14 × 10−67.37 × 10−4
Continuous variations in the substrate concentration (15%)2.00 × 10−62.47 × 10−68.17 × 10−4
20% of error in model parameters ( and )1.98 × 10−62.70 × 10−69.51 × 10−4
20% lesser in the initial nominal operating conditions in , , and 1.83 × 10−62.25 × 10−63.80 × 10−4
Normally distributed noise with zero mean and variance of 0.2 in and 1.93 × 10−62.35 × 10−67.51 × 10−4