Analytical Reduction of Nonlinear Metabolic Networks Accounting for Dynamics in Enzymatic Reactions

Table 1

Parameter estimation for system (71), rewritten as (62). The estimation of these parameters only requires the slow dynamics of the toy network in Figure 3.

	Theoretical value	Initial guess	Estimated value	Units	Error percent
1	0.110	0.010	0.072	g(L·min)^−1	34.54
2	2.000	1.000	1.298	g·L^−1	35.10
3	0.010	0.010	0.011	min− 1	10.00
4	0.110	0.010	0.073	g(L·min)^−1	33.63
5	0.013	0.010	0.006	g(L·min)^−1	53.85
6	2.000	1.000	2.143	g·L− 1	7.15
7	0.013	0.010	0.016	g(L·min)^−1	23.08