Research Article

Analytical Reduction of Nonlinear Metabolic Networks Accounting for Dynamics in Enzymatic Reactions

Table 6

Rates are in h−1·mM·B−1. Typical concentrations in Table 5 were used to estimate the consumption rates for GAP and PEP in the lipid synthesis reaction.

CompoundProduction rateConsumption rateSubnetwork

Carbohydrates7.00 × 1016.50 × 100Carbohydrate synthesis
G6P2.24 × 1021.03 × 101Upper glycolysis
6.50 × 1007.00 × 101Lipid synthesis
PEP4.37 × 1025.00 × 100Lower glycolysis
9.97 × 1001.04 × 102Lipid synthesis
GAP2.06 × 1014.47 × 102Upper glycolysis
5.00 × 1004.37 × 102Upper glycolysis
6.00 × 10−11.88 × 101Lipid synthesis