Using Graph Theory to Assess the Interaction between Cerebral Function, Brain Hemodynamics, and Systemic Variables in Premature Infants

Figure 7

Changes in the physiological network, assessed using a graph model , for one neonate in the group of study (PMA 30 weeks, 1.0 mg·kg⁻¹) at three different time instances: plots (a), (b), and (c) illustrate the edge weights for t = 10, 30, and 180 minutes after propofol administration, respectively. The graph model was constructed using defined in (2). Under each graph, the average graph degree is presented in a time frame starting right after propofol administration (t = 0) up to 6 hours after. The average graph degree measures the average connection strength of the graph edges. From (a) to (c), the edge weights increase, which translates in an increased .

(a) 10 minutes after propofol

(b) 30 minutes after propofol

(c) 3 hours after propofol