An Optimal Algorithm for Determining Risk Factors for Complex Diseases: Depressive Disorder, Osteoporosis, and Fracture in Young Patients with Breast Cancer Receiving Curative Surgery

Table 1

Demographic information of study sample ().

Variable	Mean (SD)		%
Age (yrs)	34.6 (3.7)
CCI	1.9 (3.0)
Comorbidities:
Diabetes mellitus (DM)		69	1.7
Hypertension		72	1.8
Heart failure		27	.7
Coronary heart diseases (CHD)		20	.5
Cerebrovascular diseases		18	.4
Autoimmune diseases		95	2.3
Kidney diseases		36	.9
Renal diseases		17	.4
Liver cirrhosis		12	.3
COPD		216	5.3
Distant metastatic		550	13.4
Primary metastatic		284	6.9
Adjuvant therapies:
Chemotherapy		2165	52.7
Radiotherapy		983	23.9
Tamoxifen		2623	63.9
AIs		309	7.5
Trastuzumab		132	3.2
Outcome variables:
Depression disorders		126	3.1
Fracture		31	.7
Osteoporosis		71	1.7

CCI: Charlson comorbidity index; COPD: chronic obstructive pulmonary disease; AIs: aromatase inhibitors.