Research Article
Dynamic Modeling of the Angiogenic Switch and Its Inhibition by Bevacizumab
Table 5
Sensitivities (
) of the model to the changes of parameters
, , , , , , , , , and
in the no-therapy case. One unit is
.
| | -20% | -10% | -5% | +5% | +10% | +20% |
| | 0.1321 | 0.0240 | 0.0052 | 0.0040 | 0.0143 | 0.0462 | | 0.4715 | 0.1601 | 0.0467 | 0.0640 | 0.2996 | 1.6456 | | 0.0653 | 0.0173 | 0.0044 | 0.0047 | 0.0193 | 0.0821 | | 0.0072 | 0.0017 | 0.0004 | 0.0004 | 0.0016 | 0.0061 | | 0.2287 | 0.0769 | 0.0224 | 0.0309 | 0.1454 | 0.8147 | | 0.2287 | 0.0769 | 0.0224 | 0.0309 | 0.1454 | 0.8148 | | 0.5561 | 0.0868 | 0.0176 | 0.0120 | 0.0405 | 0.1185 | | 0 | 0 | 0 | 0 | 0 | 0 |
|
|