Calculation of Free Energy Consumption in Gene Transcription with Complex Promoter Structure

Figure 3

(a) Schematic diagram for a gene model with the promoter having one ON and multiple OFFs. These chromatin states form a loop and transition from one state to its neighboring state with a constant transition rate. (b) Schematic diagram for a gene model with the promoter having one OFF and multiple ONs. These promoter states also form a loop and transition from one state to another state with a constant transition rate.

(a)

(b)